CURRICULUM VITA

Education

bulletB.S., Biology and Chemistry, Osmania University, India, 1977
bulletM.Sc., Organic Chemistry, Osmania University, India, 1979
bulletPh.D., Biochemistry, University of North Texas, Denton, Texas, 1988
bulletRobert A. Welch Foundation Postdoctoral Fellow, University of North Texas, Denton, Texas, 1988-89
bulletResearch Associate, University of Texas at Dallas, Richardson, Texas, 1991-94

Fields of Research Specialization

bulletEnzyme Mechanisms
bulletTissue Metabolism

Recent Representative Publications

Radford, B.N., Fina, M., Benjamin, J. L, Moreadith, W.R., Graves, H.K, Zhao, P., Gavva, S., Wiethoff, A., Sherry, A.D., Malloy, R.M. and Williams, R. S., "Cardioprotective Effects of 70- kDa Heat Shock Protein in Transgenic Mice", Proc. Natl. Acad. Sci. USA, 93, 2339-2342 (1996).

Karsten, W.E., Gavva, S.R., Park, S.H. and Cook, P.F., "Metal Ion Activator Effects on Intrinsic Isotope Effects for Hydride Transfer and Decarboxylation in the Reaction Catalysed by the NAD - Malic Enzyme from Ascaris Suum", Biochemistry, 34, 3253-3260 (1995).

Gavva, S.R, Weithoff, A.J., Zhao, P., Malloy, C.R. and Sherry, A.D., "A 13C Isotopomer NMR Method for Monitoring Incomplete beta-Oxidation of Fatty Acids in Intact Tissue", Biochemical Journal, 303, 847-853 (1994).

Sherry, A.D., Sumegi, B., Miller, B., Cottam, L.G., Gavva, S.R., Jones, J.G. and Malloy, C.R., "Orientation - Conserved Transfer of Symmetric Krebs Cycle Intermediates in Mammalian Tissues", Biochemistry, 33, 6268-6275 (1994).

Gavva, S.R., Harris, B.G., Weiss, P.M. and Cook, P.M., "Modification of a Thiol at the Active site of the Ascaris suum NAD- Malic Enzyme Results in Changes in the Rate-Determining Steps for Oxidative Decarboxylation of L-Malate", Biochemistry 30, 5764-5769 (1991).

Weiss, P.M., Gavva, S.R, Harris, B.G., Urbauer, J.L, Cleland, W.W.and Cook, P.F., "Mutiple Isotope Effects with Alternate Dinucleotide Substrates as a Probe of the Malic Enzyme Reaction", Biochemisty 30,5755-5763(1991).

Bhatnagar, A., Das, B., Gavva, S.R., Cook, P.F., and Srivastava, S.K., "The Kinetic Mechanism of Human Placental Aldose Reductase and Aldehyde Reductase II", Arch. Biochem. Biophys. 261, 264 - 274 (1988).